Things I can see that are different (aside from the obvious art changes)
Doc Ock magnet now the newer bigger type as used on TWD
Big plastic over the Sandman area looks to have some sort of metal cliffy on it, originals were prone to breaking
Cant see anything that would show how the Green Goblin toy would move, looks like it might just be static now
If they priced it at Pro level I think it would sell decently, at a premium point not so much, originals aren't exactly rare or overly expensive either.